Pre-operative haematological assessment in patients scheduled for major surgery

Anaesthesia. 2016 Jan:71 Suppl 1:19-28. doi: 10.1111/anae.13304.

Abstract

Peri-operative anaemia, blood loss and allogeneic blood transfusion are associated with increased postoperative morbidity and mortality, and prolonged hospital stay. A multidisciplinary, multimodal, individualised strategy, collectively termed 'patient blood management', may reduce or eliminate allogeneic blood transfusion and improve outcomes. This approach has three objectives: the detection and treatment of peri-operative anaemia; the reduction of peri-operative bleeding and coagulopathy; and harnessing and optimising the physiological tolerance of anaemia. This review focuses on the pre-operative evaluation of erythropoiesis, coagulation status and platelet function. Where possible, evidence is graded systematically and recommended therapies follow recently published consensus guidance.

Publication types

  • Review

MeSH terms

  • Anemia / diagnosis*
  • Anemia / therapy*
  • Blood Coagulation Disorders / diagnosis*
  • Blood Coagulation Disorders / therapy*
  • Blood Loss, Surgical / prevention & control
  • Humans
  • Postoperative Complications / prevention & control*
  • Preoperative Care / methods*