Clinical and patient-reported outcomes of Chinese patients undergoing haemodialysis in hospital or in the community: A 1-year longitudinal study

Nephrology (Carlton). 2016 Jul;21(7):617-23. doi: 10.1111/nep.12686.

Abstract

Aim: Little is known about the effect of haemodialysis (HD) setting on outcomes of patients with end stage renal disease (ESRD). The study aimed at comparing clinical outcomes and patient-reported outcomes (PRO) of patients on community-based (CBHD) and hospital-based haemodialysis (HBHD).

Methods: A prospective cohort of Chinese ESRD patients receiving HBHD (n = 89) or CBHD (n = 117) in Hong Kong were followed up for 12 months. Subjects were assessed on clinical outcomes of dialysis adequacy (Kt/V) and blood haemoglobin and PRO of health-related quality of life (SF-12v2), general health condition (Global Rating Scale (GRS)) and confidence to cope with their illness (Patient Enablement Instrument (PEI)). Differences between groups were analyzed by independent t-tests for the SF-12v2, GRS and PEI scores. χ(2) tests were used to analyze the difference in proportion of patients reaching the targets of Kt/V and blood haemoglobin and with GRS > 0 and PEI > 0. Multiple linear and logistic regressions were performed to assess the adjusted difference-in-difference estimation.

Results: The mean PEI and GRS scores of CBHD patients at 12 months were significantly higher than those of HBHD patients. CBHD patients had significantly greater improvement in self-efficacy and were more likely to be enabled after 12 months than the HBHD patients.

Conclusion: The study showed similar clinical outcomes and PRO between CBHD and HBHD but CBHD was more effective than HBHD in promoting patient enablement over a 12-month period. The results suggest added value for patients receiving CBHD and support the transfer of HD care from the hospital to the community.

Keywords: community centre; end stage renal disease; haemodialysis; hospital; quality of care.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Aged
  • Biomarkers / blood
  • Chi-Square Distribution
  • Community Health Services*
  • Female
  • Health Status
  • Hemoglobins / metabolism
  • Hong Kong
  • Hospitalization*
  • Humans
  • Kidney Failure, Chronic / blood
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / psychology
  • Kidney Failure, Chronic / therapy*
  • Linear Models
  • Logistic Models
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Patient Reported Outcome Measures*
  • Process Assessment, Health Care*
  • Prospective Studies
  • Quality of Life
  • Renal Dialysis*
  • Risk Factors
  • Self Efficacy
  • Time Factors
  • Treatment Outcome

Substances

  • Biomarkers
  • Hemoglobins