Anterior chamber migration of dexamethasone intravitreal implant (Ozurdex®) through basal iridectomy (Ando) in a pseudophakic patient

Eur J Ophthalmol. 2016 Apr 12;26(3):e52-4. doi: 10.5301/ejo.5000715.

Abstract

Purpose: Intravitreal implantation of dexamethasone implant (Ozurdex®) is being widely used for the treatment of macular edema (ME) after branch or central retinal vein occlusion, diabetic ME, and persistent ME associated with uveitis or Irvine-Gass syndrome. We describe a complication: migration of the dexamethasone implant into the anterior chamber through basal iridectomy (Ando) in a pseudophakic patient with development of corneal edema and secondary high intraocular pressure.

Methods: This is a case report of migration of Ozurdex® through basal iridectomy in a pseudophakic patient with iris claw lens.

Conclusions: Pseudophakic patients, with a history of vitrectomy, even those with a basal iridectomy (Ando), are at high risk for migration of the Ozurdex® into the anterior chamber and development of corneal edema.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anterior Chamber / pathology*
  • Corneal Edema / etiology
  • Dexamethasone / administration & dosage*
  • Drug Implants / adverse effects*
  • Glucocorticoids / administration & dosage*
  • Humans
  • Intravitreal Injections
  • Iridectomy*
  • Lens Implantation, Intraocular
  • Macular Edema / drug therapy
  • Male
  • Ocular Hypertension / etiology
  • Phacoemulsification
  • Prosthesis Failure / etiology*
  • Pseudophakia / etiology*

Substances

  • Drug Implants
  • Glucocorticoids
  • Dexamethasone