Dendrimer porphyrin-coated gold nanoshells for the synergistic combination of photodynamic and photothermal therapy

Ui Seok Chung; Joo-Ho Kim; Byeonggwan Kim; Eunkyoung Kim; Woo-Dong Jang; Won-Gun Koh

doi:10.1039/c5cc09149g

Dendrimer porphyrin-coated gold nanoshells for the synergistic combination of photodynamic and photothermal therapy

Chem Commun (Camb). 2016 Jan 21;52(6):1258-61. doi: 10.1039/c5cc09149g.

Authors

Ui Seok Chung¹, Joo-Ho Kim², Byeonggwan Kim¹, Eunkyoung Kim¹, Woo-Dong Jang², Won-Gun Koh¹

Affiliations

¹ Department of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemoon-gu, Seoul 120-749, Republic of Korea. wdjang@yonsei.ac.kr.
² Department of Chemistry, Yonsei University, 50 Yonsei-ro, Seodaemoon-gu, Seoul 120-749, Republic of Korea.

PMID: 26610400
DOI: 10.1039/c5cc09149g

Abstract

A dendrimer porphyrin (DP)-coated gold nanoshell (AuNS-DP) was prepared for the synergistic combination of photodyanmic and photothermal therapy. The resultant AuNS-DP successfully exhibited the generation of reactive oxygen species (ROS) as well as photothermal effect for the simultaneous application of photodynamic therapy (PDT) and photothermal therapy (PTT).

Publication types

Research Support, Non-U.S. Gov't