Seroprevalence in Chickens against Campylobacter jejuni Flagellar Capping Protein (FliD) in Selected Areas of the United States

Zoonoses Public Health. 2016 Jun;63(4):265-70. doi: 10.1111/zph.12237. Epub 2015 Nov 25.

Abstract

Campylobacter jejuni is a causative pathogen of human acute bacterial gastroenteritis. Infected poultry products are regarded as a major source for human C. jejuni infection. The flagellar capping protein (FliD) is highly conserved among C. jejuni strains/isolates and is antigenic as analysed by immunoblot. In this study, we used the FliD protein as a probe to survey the prevalence of C. jejuni antibodies in chickens from two areas in the United States. A total of 394 samples were tested. Sera from layer breeders of 44-52 weeks of age tested 100% positive, while 4- to 6-week broilers from 22 premises showed 7-100% positivity. These results demonstrate that anti-FliD antibodies were prevalent in the poultry population in the areas of serum samples collected.

Keywords: Campylobacter jejuni; FliD; flagellar capping protein; food-borne pathogen; zoonosis.

MeSH terms

  • Animals
  • Antibodies, Bacterial / blood*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / immunology
  • Bacterial Proteins / metabolism*
  • Campylobacter Infections / blood
  • Campylobacter Infections / epidemiology
  • Campylobacter Infections / immunology
  • Campylobacter Infections / veterinary*
  • Campylobacter jejuni / genetics
  • Campylobacter jejuni / metabolism*
  • Chickens* / blood
  • Seroepidemiologic Studies
  • United States / epidemiology
  • Zoonoses

Substances

  • Antibodies, Bacterial
  • Bacterial Proteins
  • FlaD protein, Bacteria