Potential Contribution of Cytomegalovirus Infection to Prenatal and Early Neonatal Mortality of Monkeys in the Adler Breeding Center

Bull Exp Biol Med. 2015 Nov;160(1):88-90. doi: 10.1007/s10517-015-3105-4. Epub 2015 Nov 25.

Abstract

Scrapings from the cervical canals and uterine cavities of females with a history of miscarriages, pathological deliveries, and stillbirths were tested for the cytomegalovirus DNA. The incidence of the agent in the females with a history of gestosis and abnormal deliveries was significantly higher than in females without anamnesis of this kind. Parenchymatous organs of stillborn neonates and animals dead during the first month of life were studied. This analysis and studies of the umbilical cords and placentas showed generalized cytomegalovirus infection in 22% dead animals, which objectively proved intrauterine infection.

Keywords: cytomegalovirus infection; monkeys; pregnancy and labor abnormalities.

MeSH terms

  • Abortion, Veterinary / etiology
  • Abortion, Veterinary / virology*
  • Animal Husbandry
  • Animals
  • Animals, Newborn
  • Causality
  • Cervix Uteri / virology
  • Chlorocebus aethiops
  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus Infections / mortality
  • Cytomegalovirus Infections / veterinary*
  • DNA, Viral / analysis
  • Female
  • Macaca
  • Male
  • Obstetric Labor Complications / veterinary
  • Obstetric Labor Complications / virology
  • Papio
  • Placenta / virology
  • Pregnancy
  • Pregnancy Complications, Infectious / veterinary*
  • Pregnancy Complications, Infectious / virology
  • Primate Diseases / mortality*
  • Russia / epidemiology
  • Stillbirth / veterinary*
  • Umbilical Cord / virology
  • Urethra / virology
  • Uterus / virology
  • Viscera / virology

Substances

  • DNA, Viral