[The use of deoxycholic acid (ATX-101) in aesthetic medicine: A promising treatment]

Rev Stomatol Chir Maxillofac Chir Orale. 2015 Dec;116(6):350-2. doi: 10.1016/j.revsto.2015.09.003. Epub 2015 Dec 1.
[Article in French]

Abstract

ATX-101 is a synthetic derivative from deoxycholic acid, which leads to destruction of adipocytes and to a skin retraction. The US Food and Drug Administration (FDA) has authorized ATX-101 injections for reduction of moderate to severe submental fat. The purpose of this note is to review the data of literature regarding the deoxycholic acid (ATX-101) where a significant difference for the submental fat between the treated group and the placebo group according to clinical and morphological criteria was observed (Refine Study 1 and 2). Side effects of this molecule seems to be limited.

Keywords: Acide désoxycholique; Deoxycholic acid; Lipolyse; Lipolysis; Liposuccion; Liposuction; Lypolyse; Sous-mentale; Submental.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Deoxycholic Acid / adverse effects
  • Deoxycholic Acid / therapeutic use*
  • Esthetics
  • Genioplasty / methods
  • Humans
  • Lipectomy / methods
  • Randomized Controlled Trials as Topic
  • Surgery, Plastic / methods
  • Surgery, Plastic / trends*
  • United States

Substances

  • ATX-101 compound
  • Deoxycholic Acid