Is chlorhexidine-methacrylate as effective as chlorhexidine digluconate in preserving resin dentin interfaces?

J Dent. 2016 Feb:45:7-13. doi: 10.1016/j.jdent.2015.11.002. Epub 2015 Dec 1.

Abstract

Objectives: The aim of the current study was to evaluate the effect of 2% CHX and 2% CHX-methacrylate compared to the resin-dentin bonds created by a two-step etch-and-rinse adhesive system after 24h, 6min and 12min.

Methods: Microtensile bond strengths and interfacial nanoleakage within resin-dentin interfaces created by Adper Single Bond 2, with or without CHX or CHX-methacrylate pre-treatment for 30s on acid-etched dentin surfaces, were evaluated after 24h, 6min and 12min of storage in distilled water at 37°C.

Results: Twelve months of storage resulted in a significant decrease in microtensile bond strength in the control group, and significant increases in silver nanoleakage. In contrast, Single Bond 2+CHX, and to a greater extent CHX-methacrylate, significantly reduced the rate of deterioration of resin-dentin interfaces over the 12min water storage period, in terms of bond strength.

Conclusions: Similar to Single Bond 2+CHX, Single Bond+CHX-methacrylates reduced the degradation of resin-bonded interfaces over a 12 month storage period. Thus it can be concluded that Single Bond 2+CHX-methacrylate may be important to improve durability of bonded interfaces and therefore, prolong the life span of adhesive restorations.

Clinical significance: Although CHX primers have been shown to enhance the durability of etch-and-rinse adhesives, that protection is lost after 2h. The use of CHX-methacrylate should last much longer since it may copolymerize with adhesive monomers, unlike CHX.

Keywords: Bond strength; Chlorhexidine digluconate; Chlorhexidine-methacrylate; Dentin; Nanoleakage.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acid Etching, Dental / methods
  • Anti-Infective Agents, Local / pharmacology*
  • Bisphenol A-Glycidyl Methacrylate / chemistry
  • Chlorhexidine / analogs & derivatives*
  • Chlorhexidine / chemistry
  • Dental Bonding
  • Dental Cements / chemistry
  • Dental Leakage
  • Dental Materials / chemistry*
  • Dental Stress Analysis
  • Dentin / drug effects
  • Dentin-Bonding Agents / chemistry
  • Humans
  • Methacrylates / chemistry*
  • Molar, Third
  • Resins, Synthetic / chemistry*
  • Surface Properties

Substances

  • Adper single bond 2
  • Anti-Infective Agents, Local
  • Dental Cements
  • Dental Materials
  • Dentin-Bonding Agents
  • Methacrylates
  • Resins, Synthetic
  • single bond
  • Bisphenol A-Glycidyl Methacrylate
  • chlorhexidine gluconate
  • Chlorhexidine