MicroRNAs, class of the small RNA containing approximately 22 nucleotides take part in regulation of metabolism of skeletal muscles as enzymes, hormones and transcription factors. They are able to regulate the intensity of the translation process through complementary. interaction with mRNA. The review presents the results of studies published in the last two years, which increase the knowledge of the effects of microRNAs on the key stages of protein synthesis in skeletal muscle. The main attention is paid to achievements which open and specify a microRNA role in regulation of the signaling pathways that coordinate intracellular metabolism of skeletal muscles at different finctionni onneiilinnc nf then