Analytical applications of MIPs in diagnostic assays: future perspectives

Anal Bioanal Chem. 2016 Mar;408(7):1735-51. doi: 10.1007/s00216-015-9137-9. Epub 2015 Nov 21.

Abstract

Many efforts have been made to produce artificial materials with biomimetic properties for applications in binding assays. Among these efforts, the technique of molecular imprinting has received much attention because of the high selectivity obtainable for molecules of interest, robustness of the produced polymers, simple and short synthesis, and excellent cost efficiency. In this review, progress in the field of molecularly imprinted sorbent assays is discussed-with a focus on work conducted from 2005 to date.

Keywords: BELISA; Fluoroimmunoassay; Immunoassay; Molecularly imprinted polymers; Molecularly imprinted sorbent assay; Radioassay.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biomarkers / analysis
  • Chemistry Techniques, Analytical / instrumentation
  • Chemistry Techniques, Analytical / methods*
  • Diagnostic Techniques and Procedures / instrumentation
  • Enzyme-Linked Immunosorbent Assay / instrumentation
  • Enzyme-Linked Immunosorbent Assay / methods
  • Equipment Design
  • Humans
  • Membranes, Artificial
  • Molecular Imprinting / instrumentation
  • Molecular Imprinting / methods*
  • Polymers / chemistry
  • Spectrometry, Fluorescence / instrumentation
  • Spectrometry, Fluorescence / methods

Substances

  • Biomarkers
  • Membranes, Artificial
  • Polymers