Transplantation of kidneys with tumors

J Nephrol. 2016 Apr;29(2):163-168. doi: 10.1007/s40620-015-0249-2. Epub 2015 Nov 20.

Abstract

The shortage of donors in the face of the increasing number of patients wait-listed for renal transplantation has prompted several strategies including the use of kidneys with a tumor, whether found by chance on harvesting from a deceased donor or intentionally removed from a living donor and transplanted after excision of the lesion. Current evidence suggests that a solitary well-differentiated renal cell carcinoma, Fuhrman nuclear grade I-II, less than 1 cm in diameter and resected before grafting may be considered at minimal risk of recurrence in the recipient who, however, should be informed of the possible risk and consent to receive such a graft.

Keywords: Kidney donation; Renal cancer; Renal transplantation; Safety of donation; Tumor transmission.

Publication types

  • Review

MeSH terms

  • Donor Selection*
  • Humans
  • Kidney Neoplasms / complications
  • Kidney Neoplasms / diagnosis*
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / surgery
  • Kidney Transplantation / adverse effects
  • Kidney Transplantation / methods*
  • Neoplasm Grading
  • Neoplasm Recurrence, Local
  • Risk Assessment
  • Risk Factors
  • Tissue Donors / supply & distribution*
  • Treatment Outcome
  • Tumor Burden
  • Waiting Lists