Factors Associated with Severe Leptospirosis, Martinique, 2010-2013

Emerg Infect Dis. 2015 Dec;21(12):2221-4. doi: 10.3201/eid2112.141099.

Abstract

To identify factors associated with disease severity, we examined 102 patients with quantitative PCR-confirmed leptospirosis in Martinique during 2010-2013. Associated factors were hypotension, chest auscultation abnormalities, icterus, oligo/anuria, thrombocytopenia, prothrombin time <68%, high levels of leptospiremia, and infection with L. interrogans serovar Icterohaemorrhagiae/Copenhageni.

Keywords: Leptospira interrogans; Martinique; bacteria; leptospiremia; qPCR; quantitative PCR; serogroup Icterohaemorrhagiae; severe leptospirosis.

MeSH terms

  • Adult
  • Animals
  • Disease Outbreaks*
  • Dog Diseases / epidemiology
  • Dog Diseases / genetics
  • Dog Diseases / pathology
  • Dogs
  • Female
  • Humans
  • Leptospirosis / blood
  • Leptospirosis / epidemiology*
  • Leptospirosis / genetics
  • Male
  • Martinique / epidemiology
  • Middle Aged
  • Zoonoses / epidemiology