NUTRITIONAL SUPPLEMENTATION IN AGE-RELATED MACULAR DEGENERATION

Retina. 2016 Jun;36(6):1119-25. doi: 10.1097/IAE.0000000000000852.

Abstract

Purpose: To evaluate the rate of adherence to prescribed nutritional supplementation in patients affected by age-related macular degeneration, in an Italian tertiary referral tertiary center.

Methods: Patients with age-related macular degeneration, age-related eye disease study Categories 3 and 4, were recruited and underwent an 11-item questionnaire.

Results: The study included a total of 193 patients meeting the age-related eye disease study nutritional supplementation criteria (174 patients with age-related eye disease study Category 4 and 19 with Category 3). Seventy-seven (40%) were taking oral supplementation, 70 of whom (90%) 1 tablet/day. Oral supplementation was recommended by the personal ophthalmologist in 85 patients (44%), including all those currently receiving it. Eight patients of 85 (9.4%) rejected supplementation despite it being recommended, mostly because they were already taking other medicines. Ninety-four patients (48%) claimed they had not received any information from their ophthalmologist.

Conclusion: Our data reveal that Italian patients with age-related eye disease study Categories 3 and 4 have a low adherence to nutritional supplementation. In 65% of cases, patients were not adequately informed by their ophthalmologist of the potential benefits of oral supplementation for age-related macular degeneration; indeed, 108 patients (56%) were not even aware such nutritional treatments are available. Ophthalmologists should be aware of the importance of giving advice to persons with age-related macular degeneration regarding the benefits of oral supplements.

MeSH terms

  • Administration, Oral
  • Aged
  • Aged, 80 and over
  • Antioxidants / administration & dosage*
  • Ascorbic Acid / administration & dosage
  • Cross-Sectional Studies
  • Dietary Supplements*
  • Disease Progression
  • Fatty Acids, Omega-3 / administration & dosage
  • Female
  • Humans
  • Italy
  • Macular Degeneration / diagnosis
  • Macular Degeneration / prevention & control*
  • Male
  • Middle Aged
  • Nutritional Physiological Phenomena
  • Patient Compliance / statistics & numerical data*
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Surveys and Questionnaires
  • Vitamins / administration & dosage*
  • Zinc / administration & dosage
  • beta Carotene / administration & dosage

Substances

  • Antioxidants
  • Fatty Acids, Omega-3
  • Vitamins
  • beta Carotene
  • Zinc
  • Ascorbic Acid