Gabapentin Use in the Neonatal Intensive Care Unit

J Pediatr. 2016 Feb:169:310-2. doi: 10.1016/j.jpeds.2015.10.013. Epub 2015 Nov 11.

Abstract

Gabapentin was used for the treatment of term and preterm infants with suspected visceral hyperalgesia caused by a variety of neurologic and gastrointestinal morbidities. Improved feeding tolerance and decreased irritability were seen, as well as decreased usage of opioids and benzodiazepines. Adverse events occurred with abrupt discontinuation of this medication.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Amines / administration & dosage*
  • Amines / adverse effects
  • Analgesics / administration & dosage*
  • Analgesics / adverse effects
  • Benzodiazepines / administration & dosage*
  • Benzodiazepines / adverse effects
  • Cyclohexanecarboxylic Acids / administration & dosage*
  • Cyclohexanecarboxylic Acids / adverse effects
  • Female
  • Gabapentin
  • Humans
  • Hyperalgesia / drug therapy*
  • Infant, Newborn
  • Intensive Care Units, Neonatal / statistics & numerical data*
  • Male
  • Retrospective Studies
  • gamma-Aminobutyric Acid / administration & dosage*
  • gamma-Aminobutyric Acid / adverse effects

Substances

  • Amines
  • Analgesics
  • Cyclohexanecarboxylic Acids
  • Benzodiazepines
  • gamma-Aminobutyric Acid
  • Gabapentin