Liver transplantation for hepatocellular carcinoma - factors influencing outcome and disease-free survival

René Fahrner; Felix Dondorf; Michael Ardelt; Yves Dittmar; Utz Settmacher; Falk Rauchfuß

doi:10.3748/wjg.v21.i42.12071

Liver transplantation for hepatocellular carcinoma - factors influencing outcome and disease-free survival

World J Gastroenterol. 2015 Nov 14;21(42):12071-82. doi: 10.3748/wjg.v21.i42.12071.

Authors

René Fahrner¹, Felix Dondorf¹, Michael Ardelt¹, Yves Dittmar¹, Utz Settmacher¹, Falk Rauchfuß¹

Affiliation

¹ René Fahrner, Felix Dondorf, Michael Ardelt, Yves Dittmar, Utz Settmacher, Falk Rauchfuß, Department of General, Visceral and Vascular Surgery, Jena University Hospital, 07740 Jena, Germany.

Abstract

Hepatocellular carcinoma is one of the leading causes of cancer-related death worldwide. Liver transplantation can be a curative treatment in selected patients. However, there are several factors that influence disease-free survival after transplantation. This review addresses the pre-, intra- and postoperative factors that influence the risk of tumor recurrence after liver transplantation.

Keywords: Diagnostics; Hepatocellular carcinoma; Liver transplantation; Recurrence; Risk factor; Survival.

Publication types

Review

MeSH terms

Carcinoma, Hepatocellular / mortality
Carcinoma, Hepatocellular / pathology
Carcinoma, Hepatocellular / surgery*
Chemotherapy, Adjuvant
Disease Progression
Disease-Free Survival
Humans
Immunosuppressive Agents / therapeutic use
Liver Neoplasms / mortality
Liver Neoplasms / pathology
Liver Neoplasms / surgery*
Liver Transplantation / adverse effects
Liver Transplantation / mortality
Neoplasm Recurrence, Local
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome

Substances

Immunosuppressive Agents