Glucose sensors based on electrospun nanofibers: a review

Anal Bioanal Chem. 2016 Feb;408(5):1285-306. doi: 10.1007/s00216-015-9152-x. Epub 2015 Nov 14.

Abstract

The worldwide increase in the number of people suffering from diabetes has been the driving force for the development of glucose sensors. The recent past has devised various approaches to formulate glucose sensors using various nanostructure materials. This review presents a combined survey of these various approaches, with emphasis on the current progress in the use of electrospun nanofibers and their composites. Outstanding characteristics of electrospun nanofibers, including high surface area, porosity, flexibility, cost effectiveness, and portable nature, make them a good choice for sensor applications. Particularly, their nature of possessing a high surface area makes them the right fit for large immobilization sites, resulting in increased interaction with analytes. Thus, these electrospun nanofiber-based glucose sensors present a number of advantages, including increased life time, which is greatly needed for practical applications. Taking all these facts into consideration, we have highlighted the latest significant developments in the field of glucose sensors across diverse approaches.

Keywords: Biosensors; Electrospinning; Glucose; Nanofibers; Nanomaterials.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biosensing Techniques / instrumentation*
  • Electrochemical Techniques / methods*
  • Glucose / chemistry*
  • Humans
  • Nanofibers / chemistry*
  • Nanotechnology / instrumentation*

Substances

  • Glucose