Massive placental perivillous fibrinoid deposition in the placenta is thought to be an immune-related condition associated with poor perinatal outcomes, including growth restriction and intrauterine fetal demise, with a high risk of recurrence. Rare cases have been associated with Coxsackievirus infection. We present such a case and review the literature.
Keywords: Coxsackievirus A16 infection; hand-foot-mouth disease; intrauterine fetal death; massive placental perivillous fibrinoid deposition.