Gender-Related Effect in Oxygenation Dynamics by Using Far-Infrared Intervention with Near-Infrared Spectroscopy Measurement: A Gender Differences Controlled Trial

PLoS One. 2015 Nov 10;10(11):e0135166. doi: 10.1371/journal.pone.0135166. eCollection 2015.

Abstract

Many studies have indicated the microcirculation can directly respond to disease-related symptoms. However, the capacity of microcirculation would vary due to the gender differences. Near-infrared spectroscopy (NIRS) is a noninvasive technique to monitor tissue oxygenation dynamics. In this study, the far-infrared (FIR) source was used for physiological intervention of microcirculation. The experimental results show that the nature difference of oxygenation status exists between male and female during FIR irradiation. Therefore, we suggest the NIRS-based assessment should be calibrated with the gender-related effect for clinical diagnosis of peripheral arterial disease.

Publication types

  • Comparative Study
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Hemodynamics
  • Hemoglobinometry / methods*
  • Hemoglobins / analysis
  • Humans
  • Infrared Rays
  • Male
  • Microcirculation / physiology*
  • Oxygen Consumption
  • Oxyhemoglobins / analysis*
  • Peripheral Arterial Disease / diagnosis*
  • Peripheral Arterial Disease / physiopathology
  • Prospective Studies
  • Sex Characteristics*
  • Skin Temperature / radiation effects
  • Spectroscopy, Near-Infrared*
  • Vasodilation / radiation effects
  • Young Adult

Substances

  • Hemoglobins
  • Oxyhemoglobins

Grants and funding

This work was supported in part by the Taiwan National Science Council under Grant Nos. NSC 101-2628-E-009-026-MY3, NSC 102-2321-B-009-002, NSC 102-2622-E-009-007-CC3, NSC 102-2627-E-010-001, NSC 102-3011-P-010-003, and a grant from Ministry of Education, Aim for the Top University Plan in National Chiao-Tung University 101W9866, http://www.most.gov.tw/mp.aspx?mp=7.