[Stereotactic radiosurgery of abdominal cancer metastases. Report on the first successful extracranial radiosurgical intervention in Hungary]

Orv Hetil. 2015 Sep 27;156(39):1593-9. doi: 10.1556/650.2015.30183.
[Article in Hungarian]

Abstract

Due to the development and increasing effectiveness of novel cancer therapies, the role of local treatments in metastatic diseases have been increasing in the last decades. The aim of the authors was to present the first successful extracranial stereotactic radiosurgical intervention in Hungary. A 58-year-old male patient with gastric adenocarcinoma underwent surgery and adjuvant chemotherapy. Later, surgical removal of suprarenal gland metastases and first line chemotherapy were carried out. Four years after the first surgery a follow up computed tomographic scan revealed bifocal peritoneal metastases caudally from the edge of the liver and the left kidney with diameters of 2 cm in size. Definitive stereotactic body radiosurgery of 12 Gy single dose was performed using cone beam computed tomography image guidance and intensity modulated arc therapy with two pairs of arcs. The total duration of the procedure was only 25 min and early or late side effects were not observed. Follow up computed tomography scans performed 3 and 7 months after the intervention showed complete regression of the metastases. The authors conclude that stereotactic body radiosurgery can be a safe and effective alternative of metastasis surgery in case of slow growing oligo-metastases.

Keywords: image guided radiotherapy; intensity modulated arc therapy; intenzitásmodulált dinamikus ívbesugárzás; képvezérelt sugárterápia; oligometastases; oligometasztázis; stereotactic abdominal radiosurgery; stereotaxiás hasi sugársebészet.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / secondary
  • Adenocarcinoma / surgery*
  • Humans
  • Hungary
  • Male
  • Middle Aged
  • Organs at Risk / radiation effects
  • Peritoneal Neoplasms / diagnostic imaging
  • Peritoneal Neoplasms / secondary*
  • Peritoneal Neoplasms / surgery*
  • Radiosurgery* / methods
  • Stomach Neoplasms / pathology*
  • Tomography, X-Ray Computed
  • Treatment Outcome