Reliability of stable Pb isotopes to identify Pb sources and verifying biological fractionation of Pb isotopes in goats and chickens

Hokuto Nakata; Shouta M M Nakayama; John Yabe; Allan Liazambi; Hazuki Mizukawa; Wageh Sobhy Darwish; Yoshinori Ikenaka; Mayumi Ishizuka

doi:10.1016/j.envpol.2015.10.006

Reliability of stable Pb isotopes to identify Pb sources and verifying biological fractionation of Pb isotopes in goats and chickens

Environ Pollut. 2016 Jan;208(Pt B):395-403. doi: 10.1016/j.envpol.2015.10.006. Epub 2015 Nov 6.

Authors

Hokuto Nakata¹, Shouta M M Nakayama¹, John Yabe², Allan Liazambi³, Hazuki Mizukawa⁴, Wageh Sobhy Darwish⁵, Yoshinori Ikenaka⁶, Mayumi Ishizuka⁷

Affiliations

¹ Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan.
² The University of Zambia, School of Veterinary Medicine, P.O. Box 32379, Lusaka, Zambia.
³ Central Province Veterinary Office, Kabwe, Zambia.
⁴ Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan.
⁵ Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan; Food Control Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
⁶ Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan; Water Research Group, School of Environmental Sciences and Development, North-West University, South Africa.
⁷ Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18 Nishi 9, Kita-ku, Sapporo 060-0818, Japan. Electronic address: ishizum@vetmed.hokudai.ac.jp.

PMID: 26549754
DOI: 10.1016/j.envpol.2015.10.006

Abstract

Stable Pb isotope ratios (Pb-IRs) have been recognized as an efficient tool for identifying sources. This study carried out at Kabwe mining area, Zambia, to elucidate the presence or absence of Pb isotope fractionation in goat and chicken, to evaluate the reliability of identifying Pb pollution sources via analysis of Pb-IRs, and to assess whether a threshold for blood Pb levels (Pb-B) for biological fractionation was present. The variation of Pb-IRs in goat decreased with an increase in Pb-B and were fixed at certain values close to those of the dominant source of Pb exposure at Pb-B > 5 μg/dL. However, chickens did not show a clear relationship for Pb-IRs against Pb-B, or a fractionation threshold. Given these, the biological fractionation of Pb isotopes should not occur in chickens but in goats, and the threshold for triggering biological fractionation is at around 5 μg/dL of Pb-B in goats.

Keywords: Biological fractionation; Chicken; Goat; Pb pollution source; Stable Pb isotopes.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chickens* / blood
Environmental Monitoring
Environmental Pollution / analysis
Goats* / blood
Isotopes / analysis*
Isotopes / blood
Lead / analysis*
Lead / blood
Mining
Reproducibility of Results
Zambia

Substances

Isotopes
Lead