Atypical plasma lipid profiles in leukemia

Areeb Iqbal; Muhammad Zaid; Rimsha Munir; Hina Usman; Hubert Kalbacher; Lisa Scandiuzzi; Nousheen Zaidi

doi:10.1016/j.cca.2015.11.003

Atypical plasma lipid profiles in leukemia

Clin Chim Acta. 2016 Jan 15:452:129-33. doi: 10.1016/j.cca.2015.11.003. Epub 2015 Nov 6.

Authors

Areeb Iqbal¹, Muhammad Zaid¹, Rimsha Munir¹, Hina Usman¹, Hubert Kalbacher², Lisa Scandiuzzi³, Nousheen Zaidi⁴

Affiliations

¹ Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan.
² Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076, Tübingen, Germany.
³ Department of Radiation Oncology, 1300 Morris Park Avenue, 10461 Bronx, NY, USA.
⁴ Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan; Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076, Tübingen, Germany. Electronic address: nzzaidi@yahoo.com.

PMID: 26549657
DOI: 10.1016/j.cca.2015.11.003

Abstract

Numerous studies have reported alterations in the plasma lipid profiles of leukemia patients. However, there are several inconsistencies in these reports. The present review highlights and compiles findings from different research groups regarding association of plasma lipoprotein levels with the risk of developing leukemia. We have also discussed the clinical significance of plasma lipid profiles in management of leukemia. Furthermore, the potential role of plasma lipids in promoting leukemogenesis is also highlighted.

Keywords: Leukemia; Lipoproteins; Plasma lipids.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Biomarkers, Tumor / blood*
Humans
Leukemia / blood*
Leukemia / diagnosis
Leukemia / pathology
Lipids / blood*

Substances

Biomarkers, Tumor
Lipids