Proteomics of endometrial cancer diagnosis, treatment, and prognosis

Proteomics Clin Appl. 2016 Mar;10(3):217-29. doi: 10.1002/prca.201500055. Epub 2015 Dec 15.

Abstract

This review discusses the current status of proteomics technology in endometrial cancer diagnosis, treatment and prognosis. The first part of this review focuses on recently identified biomarkers for endometrial cancer, their importance in clinical use as well as the proteomic methods used in their discovery. The second part highlights some of the emerging mass spectrometry based proteomic technologies that promise to contribute to a better understanding of endometrial cancer by comparing the abundance of hundreds or thousands of proteins simultaneously.

Keywords: Biomarker; Endometrial cancer.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis*
  • Endometrial Neoplasms / diagnosis*
  • Endometrial Neoplasms / drug therapy*
  • Female
  • Humans
  • Mass Spectrometry
  • Neoplasm Proteins / analysis*
  • Prognosis
  • Proteomics*

Substances

  • Biomarkers, Tumor
  • Neoplasm Proteins