Emergence of Pathogenicity in Lagoviruses: Evolution from Pre-existing Nonpathogenic Strains or through a Species Jump?

Pedro José Esteves; Joana Abrantes; Stéphane Bertagnoli; Patrizia Cavadini; Dolores Gavier-Widén; Jean-Sébastien Guitton; Antonio Lavazza; Evelyne Lemaitre; Jérôme Letty; Ana Margarida Lopes; Aleksija S Neimanis; Nathalie Ruvoën-Clouet; Jacques Le Pendu; Stéphane Marchandeau; Ghislaine Le Gall-Reculé

doi:10.1371/journal.ppat.1005087

Emergence of Pathogenicity in Lagoviruses: Evolution from Pre-existing Nonpathogenic Strains or through a Species Jump?

PLoS Pathog. 2015 Nov 5;11(11):e1005087. doi: 10.1371/journal.ppat.1005087. eCollection 2015.

Authors

Pedro José Esteves^{1

2

3}, Joana Abrantes¹, Stéphane Bertagnoli^{4

5}, Patrizia Cavadini⁶, Dolores Gavier-Widén⁷, Jean-Sébastien Guitton⁸, Antonio Lavazza⁹, Evelyne Lemaitre^{10

11}, Jérôme Letty⁸, Ana Margarida Lopes^{1

2}, Aleksija S Neimanis⁷, Nathalie Ruvoën-Clouet¹², Jacques Le Pendu¹², Stéphane Marchandeau⁸, Ghislaine Le Gall-Reculé^{10

11}

Affiliations

¹ InBIO-Research Network in Biodiversity and Evolutionary Biology, CIBIO, Campus de Vairão, Universidade do Porto, Vairão, Portugal.
² Departamento de Biologia, Faculdade de Ciências da Universidade do Porto, Porto, Portugal.
³ CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Gandra, Portugal.
⁴ UMR 1225, INRA, Toulouse, France.
⁵ INP-ENVT, University of Toulouse, Toulouse, France.
⁶ Proteomic Unit, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini", Brescia, Italy.
⁷ Department of Pathology and Wildlife Diseases, National Veterinary Institute, Uppsala, Sweden.
⁸ Department of Studies and Research, National Hunting and Wildlife Agency (ONCFS), Nantes, France.
⁹ Virology Unit, Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini", Brescia, Italy.
¹⁰ Avian and Rabbit Virology Immunology Parasitology Unit, Ploufragan-Plouzané Laboratory, French Agency for Food, Environmental and Occupational Health & Safety (Anses), Ploufragan, France.
¹¹ European University of Brittany, Rennes, France.
¹² Inserm U892; CNRS, UMR 6299University of Nantes, Nantes France.

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Biological Evolution*
Genome, Bacterial / genetics*
Humans
Lagovirus / isolation & purification*
Species Specificity
Virulence / genetics*

Grants and funding

The authors are grateful to the ERA-Net anihwa (Animal Health and Welfare), a Coordination Action funded under the European Commission’s ERA-Net scheme within the Seventh Framework Programme (Contract No. 291815), for having retained the project ECALEP to come as part of the 2nd join call involving 15 European countries for the next three years. The ECALEP project is funded by the ANR (France, contracts ANR-14-ANWA-0004-01, ANR-14-ANWA-0004-02, ANR-14-ANWA-0004-03, ANR-14-ANWA-0004-04), the Ministry of Health, Dep. for Veterinary Public Health, Nutrition & Food Safety (Italy) and the Research council FORMAS (Sweden, contract FORMAS 221-2014-1841). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.