A rare case of primary cardiac lymphoma

BMJ Case Rep. 2015 Nov 4:2015:bcr2015211208. doi: 10.1136/bcr-2015-211208.

Abstract

A 71-year-old man presented with shortness of breath and tachycardia along with systemic symptoms of weight loss and lethargy. A pulmonary embolus was the initial suspected diagnosis but through extensive investigations a rarer cause of his symptoms was identified. This case demonstrates the importance of cardiac imaging in the assessment and non-invasive tissue characterisation of a suspected cardiac tumour; in our case, this was subsequently confirmed by careful histological/immunocytochemical evaluation of the pericardial effusion as a primary cardiac B-cell non-Hodgkin's lymphoma, thus enabling appropriate management leading to an excellent clinical outcome.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Combined Chemotherapy Protocols*
  • Cyclophosphamide
  • Doxorubicin
  • Dyspnea / etiology
  • Heart Neoplasms / diagnosis*
  • Heart Neoplasms / drug therapy
  • Heart Neoplasms / pathology
  • Humans
  • Lethargy / etiology
  • Lymphoma, Non-Hodgkin / diagnosis*
  • Lymphoma, Non-Hodgkin / drug therapy
  • Lymphoma, Non-Hodgkin / pathology
  • Male
  • Pericardial Effusion / drug therapy
  • Pericardial Effusion / etiology*
  • Pericardial Effusion / pathology
  • Prednisone
  • Remission Induction
  • Rituximab / administration & dosage*
  • Tachycardia / etiology
  • Treatment Outcome
  • Vincristine
  • Weight Loss

Substances

  • Rituximab
  • Vincristine
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CHOP protocol