Vogt-Koyanagi-Harada syndrome and Crohn's disease: an exceptional association

Gastroenterol Rep (Oxf). 2018 Feb 1;6(1):65-67. doi: 10.1093/gastro/gov056. Epub 2015 Nov 3.

Abstract

Vogt-Koyanagi-Harada disease (VKH) is a rare, multisystem disease of melanocyte-containing organs. It is characterized by diffuse, granulomatous inflammation involving various organs. It has been reported to occur in association with other autoimmune disorders. We report the case of a female patient who was diagnosed with VKH at the age of 4 years and who was treated with corticosteroids until the age of 16. Twenty years later, Crohn's disease was diagnosed, with a severe flare-up. Three cases of VKH associated with ulcerative colitis have previously been reported anecdotally but, to our knowledge, this is the first case occurring in association to Crohn's disease.

Keywords: Crohn’s disease; Vogt-Koyanagi-Harada disease; granulomatous inflammation.

Publication types

  • Case Reports