Recent developments in catalysts have enhanced the potential for the utilisation of carbon dioxide as a chemical feedstock. Using the appropriate energy efficient catalyst enables a range of chemical pathways leading to desirable products. In doing so, CO2 provides an economically and environmentally beneficial source of C1 feedstock, while improving the issues relating to security of supply that are associated with fossil-based feedstocks. However, the dependence on catalysts brings other supply chains into consideration, supply chains that may also have security of supply issues. The choice of chemical pathways for specific products will therefore entail an assessment not only of economic factors but also the security of supply issues for the catalysts. This is a multi-criteria decision making problem. In this paper, we present a modified 4A framework based on the framework suggested by the Asian Pacific Energy Research centre for macro-economic applications. The 4A methodology is named after the criteria used to compare alternatives: availability, acceptability, applicability and affordability. We have adapted this framework for the consideration of alternative chemical reaction processes using a micro-economic outlook. Data from a number of sources were collected and used to quantify each of the 4A criteria. A graphical representation of the assessments is used to support the decision maker in comparing alternatives. The framework not only allows for the comparison of processes but also highlights current limitations in the CCU processes. The framework presented can be used by a variety of stakeholders, including regulators, investors, and process industries, with the aim of identifying promising routes within a broader multi-criteria decision making process.