Phenylpropanoids from the stems of Ephedra sinica

J Asian Nat Prod Res. 2016;18(3):260-7. doi: 10.1080/10286020.2015.1070831. Epub 2015 Nov 3.

Abstract

Two new compounds of phenylpropanoids, (S)-N-((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-5-oxopyrrolidine-2-carboxamide (1) and (3R)-3-O-β-d-glucopyranosyl-3-phenylpropanoic acid (2), were isolated from the stems of Ephedra sinica. Their structures were elucidated by in-depth examination of spectroscopic data, mainly including those from the 1D and 2D NMR and HRESIMS techniques, and chemical method. The absolute configurations of the two compounds were also corroborated through CD procedure.

Keywords: Ephedra sinica; Ephedraceae; amphetamine-type alkaloid; glycoside of phenylpropanoic acid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Ephedra sinica / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenylpropionates / chemistry
  • Phenylpropionates / isolation & purification*
  • Plant Stems / chemistry

Substances

  • (3R)-3-O-beta-D-glucopyranosyl-3-phenylpropanoic acid
  • (S)-N-((1R,2S)-1-hydroxy-1-phenylpropan-2-yl)-5-oxopyrrolidine-2-carboxamide
  • Drugs, Chinese Herbal
  • Phenylpropionates
  • 3-phenylpropionic acid