Pain and focal masses in the foot and ankle are frequently encountered and often initiate a workup including imaging. It is important to differentiate benign lesions from aggressive benign or malignant lesions. In this review, multiple examples of osseous and soft tissue tumors of the foot and ankle will be presented. Additionally, the compartmental anatomy of the foot and ankle will be discussed in terms of its relevance for percutaneous biopsy planning and eventual surgery. Finally, a general overview of the surgical management of benign, benign aggressive and malignant tumors of the foot and ankle will be discussed.
Keywords: Anatomy; Ankle; Biopsy; Bone; Compartments; Foot; Imaging; MRI; Mass; Pain; Pathology; Percutaneous; Sarcoma; Soft tissue; Surgery; Swelling; Tumor.