Reducing Sitting Time After Stroke: A Phase II Safety and Feasibility Randomized Controlled Trial

Coralie English; Genevieve N Healy; Tim Olds; Gaynor Parfitt; Erika Borkoles; Alison Coates; Sharon Kramer; Julie Bernhardt

doi:10.1016/j.apmr.2015.10.094

Reducing Sitting Time After Stroke: A Phase II Safety and Feasibility Randomized Controlled Trial

Arch Phys Med Rehabil. 2016 Feb;97(2):273-80. doi: 10.1016/j.apmr.2015.10.094. Epub 2015 Oct 31.

Authors

Coralie English¹, Genevieve N Healy², Tim Olds³, Gaynor Parfitt³, Erika Borkoles⁴, Alison Coates³, Sharon Kramer⁵, Julie Bernhardt⁵

Affiliations

¹ Alliance for Research in Exercise, Nutrition and Activity, Sansom Institute of Health Research, University of South Australia, Adelaide, SA, Australia; Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia. Electronic address: Coralie.english@newcastle.edu.au.
² School of Public Health, The University of Queensland, Brisbane, QLD, Australia; Baker International Diabetes Institute Heart and Diabetes Institute, Melbourne, VIC, Australia; School of Physiotherapy, Curtin University, Perth, WA, Australia.
³ Alliance for Research in Exercise, Nutrition and Activity, Sansom Institute of Health Research, University of South Australia, Adelaide, SA, Australia.
⁴ Faculty of Management, Bournemouth University, Poole, Dorset, United Kingdom; College of Sport and Exercise, Victoria University, Melbourne, VIC, Australia.
⁵ Stroke Division, Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia.

PMID: 26529471
DOI: 10.1016/j.apmr.2015.10.094

Abstract

Objective: To test the safety, feasibility, and effectiveness of reducing sitting time in stroke survivors.

Design: Randomized controlled trial with attention-matched controls and blinded assessments.

Setting: Community.

Participants: Stroke survivors (N=35; 22 men; mean age, 66.9±12.7y).

Interventions: Four counseling sessions over 7 weeks with a message of sit less and move more (intervention group) or calcium for bone health (attention-matched control group).

Main outcome measures: Measures included safety (adverse events, increases in pain, spasticity, or fatigue) and feasibility (adherence to trial protocol). Secondary measures included time spent sitting (including in prolonged bouts ≥30min), standing, and stepping as measured by the thigh-worn inclinometer (7d, 24h/d protocol) and time spent in physical activity of at least moderate intensity as measured by a triaxial accelerometer. The Multimedia Activity Recall for Children and Adults was used to describe changes in use of time.

Results: Thirty-three participants completed the full protocol. Four participants reported falls during the intervention period with no other adverse events. From a baseline average of 640.7±99.6min/d, daily sitting time reduced on average by 30±50.6min/d (95% confidence interval [CI], 5.8-54.6) in the intervention group and 40.4±92.5min/d in the control group (95% CI, 13.0-93.8). Participants in both groups also reduced their time spent in prolonged sitting bouts (≥30min) and increased time spent standing and stepping.

Conclusions: Our protocol was both safe and feasible. Participants in both groups spent less time sitting and more time standing and stepping postintervention, but outcomes were not superior for intervention participants. Attention matching is desirable in clinical trials and may have contributed to the positive outcomes for control participants.

Keywords: Exercise; Rehabilitation; Sedentary lifestyle; Stroke; Walking.

Publication types

Clinical Trial, Phase II
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Accidental Falls / statistics & numerical data
Aged
Feasibility Studies
Female
Humans
Male
Motivational Interviewing
Motor Activity / physiology*
Pilot Projects
Posture / physiology*
Secondary Prevention
Stroke / physiopathology
Stroke / prevention & control
Stroke Rehabilitation*

Associated data

ANZCTR/ACTRN12612000958886