Diagnosis of prostate cancer via nanotechnological approach

Int J Nanomedicine. 2015 Oct 19:10:6555-69. doi: 10.2147/IJN.S91908. eCollection 2015.

Abstract

Prostate cancer is one of the leading causes of cancer-related deaths among the Caucasian adult males in Europe and the USA. Currently available diagnostic strategies for patients with prostate cancer are invasive and unpleasant and have poor accuracy. Many patients have been overly or underly treated resulting in a controversy regarding the reliability of current conventional diagnostic approaches. This review discusses the state-of-the-art research in the development of novel noninvasive prostate cancer diagnostics using nanotechnology coupled with suggested diagnostic strategies for their clinical implication.

Keywords: PSA; bioassay; bodily fluid; nanodevice; nanomaterial; non-PSA biomarker.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biological Assay
  • Body Fluids / metabolism
  • Humans
  • Male
  • Nanomedicine / instrumentation
  • Nanomedicine / methods*
  • Prostate-Specific Antigen / metabolism
  • Prostatic Neoplasms / diagnosis*
  • Prostatic Neoplasms / metabolism

Substances

  • Prostate-Specific Antigen