Supramolecular rulers enabling selective detection of pure short ssDNA via chiral self-assembly

Istvan Kocsis; Alexandru Rotaru; Yves-Marie Legrand; Ion Grosu; Mihail Barboiu

doi:10.1039/c5cc08283h

Supramolecular rulers enabling selective detection of pure short ssDNA via chiral self-assembly

Chem Commun (Camb). 2016 Jan 7;52(2):386-9. doi: 10.1039/c5cc08283h. Epub 2015 Nov 2.

Authors

Istvan Kocsis¹, Alexandru Rotaru, Yves-Marie Legrand, Ion Grosu, Mihail Barboiu

Affiliation

¹ Adaptive Supramolecular Nanosystems Group, Institut Européen des Membranes, University of Montpellier/ENSCM/CNRS 5635, Pl. Eugène Bataillon, CC 047, 34095 Montpellier, Cedex 5, France. mihail-dumitru.barboiu@univ-montp2.fr.

PMID: 26524684
DOI: 10.1039/c5cc08283h

Abstract

Multivalent self-assembly of trifunctional aromatic propellers and ssDNA results in the formation of chiral supramolecular assemblies that can be used for the detection of small fragments of ssDNA with different lengths and compositions.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aniline Compounds / chemistry*
DNA, Single-Stranded / analysis*
Guanidines / chemistry*
Hydrophobic and Hydrophilic Interactions
Macromolecular Substances / chemistry*
Proton Magnetic Resonance Spectroscopy
Quaternary Ammonium Compounds / chemistry*
Stereoisomerism

Substances

Aniline Compounds
DNA, Single-Stranded
Guanidines
Macromolecular Substances
Quaternary Ammonium Compounds