Low Contrast Dose Catheter-Directed CT Angiography (CCTA)

Cardiovasc Intervent Radiol. 2016 Apr;39(4):606-10. doi: 10.1007/s00270-015-1232-y. Epub 2015 Oct 30.

Abstract

Purpose: Catheter-directed computed tomography angiography (CCTA) has been shown to reduce the contrast volumes required in conventional CTA, thus minimizing the risk of contrast-induced nephropathy (CIN).

Materials and methods: A retrospective analysis was performed on cases where CCTA was used to assess access vessels prior to transfemoral aortic valve implantation (TAVI, n = 53), abdominal aortic aneurysm assessment for endovascular aneurysm repair (EVAR, n = 11), and peripheral vascular disease (PVD, n = 24).

Results: We show that CCTA can image vasculature with adequate diagnostic detail to allow assessment of lower extremity disease, anatomic suitability for EVAR, as well as potential contraindications to TAVI. Average contrast volumes for pre-TAVI, pre-EVAR, and PVD cases were 7, 11, and 28 mL, respectively.

Conclusion: This study validates the use of CCTA in obtaining diagnostic images of the abdominal and pelvic vessels and in imaging lower extremity vasculature.

Keywords: Abdominal aortic aneurysms (AAA); Aorta; Arterial intervention; Contrast media; EVAR; Intra-arterial; Peripheral vascular; TAVI.

Publication types

  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Abdomen / blood supply
  • Aged
  • Aged, 80 and over
  • Aortic Aneurysm, Abdominal / diagnostic imaging
  • Blood Vessels / diagnostic imaging*
  • Cardiovascular Diseases / diagnostic imaging*
  • Catheterization
  • Computed Tomography Angiography / methods*
  • Contrast Media / administration & dosage
  • Contrast Media / adverse effects
  • Endovascular Procedures
  • Female
  • Heart Valve Diseases / diagnostic imaging
  • Heart Valve Prosthesis Implantation
  • Humans
  • Kidney Diseases / chemically induced
  • Kidney Diseases / prevention & control
  • Male
  • Pelvis / blood supply
  • Peripheral Vascular Diseases / diagnostic imaging
  • Retrospective Studies

Substances

  • Contrast Media