Abstract
Adenovirus-induced fulminant hepatitis is rare. It has been reported in children with primary immunodeficiency, following transplantation or while receiving chemotherapy for hematological malignancy. We present the case of an infant recovering from chemotherapy for atypical teratoid rhabdoid tumor (ATRT) in whom a diagnosis of hepatic necrosis due to adenovirus was made.
Keywords:
adenovirus; atypical teratoid/rhabdoid tumor; cidofovir; hepatic necrosis.
© 2015 Japan Pediatric Society.
MeSH terms
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Adenoviridae / genetics
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Adenoviridae / isolation & purification*
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Biopsy
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Brain Neoplasms / complications*
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Brain Neoplasms / diagnosis
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DNA, Viral / analysis
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Fatal Outcome
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Hepatitis, Viral, Human / diagnosis
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Hepatitis, Viral, Human / etiology*
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Hepatitis, Viral, Human / virology
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Humans
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Infant
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Liver / pathology*
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Liver / virology
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Magnetic Resonance Imaging
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Male
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Microscopy, Electron
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Necrosis
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Polymerase Chain Reaction
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Rhabdoid Tumor / complications*
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Rhabdoid Tumor / diagnosis
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Teratoma / complications*
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Teratoma / diagnosis
Supplementary concepts
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Typical Teratoid Rhabdoid Tumor