Middle Interhemispheric Variant of Holoprosencephaly - Presenting as Non-Visualized Cavum Septum Pellucidum and An Interhemispheric Cyst in A 19-Weeks Fetus

Akhila Vasudeva; Shalini S Nayak; Rajagopal Kadavigere; Katta M Girisha; Jyothi Shetty

doi:10.7860/JCDR/2015/14076.6525

Middle Interhemispheric Variant of Holoprosencephaly - Presenting as Non-Visualized Cavum Septum Pellucidum and An Interhemispheric Cyst in A 19-Weeks Fetus

J Clin Diagn Res. 2015 Sep;9(9):QD11-3. doi: 10.7860/JCDR/2015/14076.6525. Epub 2015 Sep 1.

Authors

Akhila Vasudeva¹, Shalini S Nayak², Rajagopal Kadavigere³, Katta M Girisha⁴, Jyothi Shetty⁵

Affiliations

¹ Associate Professor, Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University , Manipal, India .
² Junior Research Fellow, Department of Medical Genetics, Kasturba Medical College, Manipal University , Manipal, India .
³ Professor and HOD, Department of Radiology, Kasturba Medical College, Manipal University , Manipal, India .
⁴ Professor and HOD, Department of Medical Genetics, Kasturba Medical College, Manipal University , Manipal, India .
⁵ Additional Professor and Chief of Unit 4, Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University , Manipal, India .

Abstract

Middle Interhemispheric variant (MIH) is a rare subtype of holoprosencephaly (HPE), also known as syntelencephaly. We present a case of MIH, which was diagnosed as an interhemispheric cyst on antenatal sonography at 19 weeks, but later diagnosed as MIH variant of holoprosencephaly after a postabortal MRI and perinatal autopsy.

Keywords: Arachnoid cyst; Interhemispheric fissure; Ventriculomegaly.

Publication types

Case Reports