Subcutaneous Infection Associated with Trichosporon ovoides: A Case Report and Review of Literature

Mycopathologia. 2016 Apr;181(3-4):285-90. doi: 10.1007/s11046-015-9958-2. Epub 2015 Oct 22.

Abstract

Trichosporon species are opportunistic yeasts which can cause infections, especially in immunocompromised patients. This is a report of Trichosporon ovoides that caused subcutaneous infection in a patient with underlying ischemic heart disease. The identification of fungal isolate was confirmed by PCR sequencing of ITS and large subunit regions in rRNA gene. In vitro susceptibility study showed that the isolate was susceptible to amphotericin B, fluconazole and voriconazole, and resistant to caspofungin, anidulafungin and itraconazole. The lesion improved after treatment with oral fluconazole and topical miconazole.

Keywords: Subcutaneous infection; Trichosporon ovoides; Trichosporonosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use*
  • DNA, Intergenic / genetics
  • Dermatomycoses / drug therapy*
  • Dermatomycoses / microbiology
  • Female
  • Fluconazole / therapeutic use
  • Humans
  • Immunocompromised Host*
  • Miconazole / therapeutic use
  • Microbial Sensitivity Tests
  • Middle Aged
  • Opportunistic Infections / drug therapy*
  • Opportunistic Infections / microbiology
  • Polymerase Chain Reaction
  • Trichosporon / drug effects*
  • Trichosporon / genetics
  • Trichosporon / isolation & purification
  • Trichosporonosis / drug therapy*
  • Trichosporonosis / microbiology

Substances

  • Antifungal Agents
  • DNA, Intergenic
  • Miconazole
  • Fluconazole