Successful Heart Transplantation for Unreversible Endomyocardial Fibrosis Related to FIP1L1-PDGFRA Chronic Eosinophilic Leukemia

Transplantation. 2015 Nov;99(11):e176-7. doi: 10.1097/TP.0000000000000939.

Authors

Fanny Fassnacht¹, Mathilde Roumier, Pierre Fouret, Vincent Levy, Shaida Varnous, Stéphanie Russel, Guillaume Lefevre, Jean Emmanuel Kahn

Affiliation

¹ 1 Department of Internal Medicine, Foch Hospital and Versailles Saint Quentin en Yvelines University, Suresnes, France. 2 Department of Pathology, Pitié-Salpetrière Hospital, and Pierre et Marie Curie University, Paris, France. 3 Clinical Research Unit and Center for Clinical Research, Avicenne Hospital and Paris XIII University, Bobigny, France. 4 Department of Thoracic and Cardiac Surgery, Pitié-Salpetrière Hospital, and Pierre et Marie Curie University, Paris, France. 5 Department of Cardiology, Foch Hospital and Versailles Saint Quentin en Yvelines University, Suresnes, France. 6 Institute of Immunology, French Eosinophil Network and Research Unit, Lille University Hospital, Université Lille Nord de France, Lille, France.

PMID: 26492057
DOI: 10.1097/TP.0000000000000939

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Antineoplastic Agents / therapeutic use
Biopsy
Cardiomyopathies / diagnosis
Cardiomyopathies / etiology
Cardiomyopathies / surgery*
Fibrosis
Heart Transplantation*
Humans
Hypereosinophilic Syndrome / complications*
Hypereosinophilic Syndrome / diagnosis
Hypereosinophilic Syndrome / drug therapy
Hypereosinophilic Syndrome / genetics
Imatinib Mesylate / therapeutic use
Leukemia
Magnetic Resonance Imaging
Male
Myocardium / pathology*
Oncogene Proteins, Fusion / genetics*
Protein Kinase Inhibitors / therapeutic use
Receptor, Platelet-Derived Growth Factor alpha / genetics*
Treatment Outcome
mRNA Cleavage and Polyadenylation Factors / genetics*

Substances

Antineoplastic Agents
Oncogene Proteins, Fusion
Protein Kinase Inhibitors
mRNA Cleavage and Polyadenylation Factors
Imatinib Mesylate
FIP1L1-PDGFRA fusion protein, human
Receptor, Platelet-Derived Growth Factor alpha

Supplementary concepts

Pdgfra-Associated Chronic Eosinophilic Leukemia