A Glimpse to Background and Characteristics of Major Molecular Biological Networks

Biomed Res Int. 2015:2015:540297. doi: 10.1155/2015/540297. Epub 2015 Sep 30.

Abstract

Recently, biology has become a data intensive science because of huge data sets produced by high throughput molecular biological experiments in diverse areas including the fields of genomics, transcriptomics, proteomics, and metabolomics. These huge datasets have paved the way for system-level analysis of the processes and subprocesses of the cell. For system-level understanding, initially the elements of a system are connected based on their mutual relations and a network is formed. Among omics researchers, construction and analysis of biological networks have become highly popular. In this review, we briefly discuss both the biological background and topological properties of major types of omics networks to facilitate a comprehensive understanding and to conceptualize the foundation of network biology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Gene Regulatory Networks*
  • Models, Biological*