Comparative Transcriptomics in Yeasts

Methods Mol Biol. 2016:1361:67-76. doi: 10.1007/978-1-4939-3079-1_4.

Abstract

Comparative functional genomics approaches have already shed an important light on the evolution of gene expression that underlies phenotypic diversity. However, comparison across many species in a phylogeny presents several major challenges. Here, we describe our experimental framework for comparative transcriptomics in a complex phylogeny.

Keywords: Comparative expression profiling; Evolution; Gene regulation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Evolution, Molecular*
  • Gene Expression Profiling / methods*
  • Gene Expression Regulation, Fungal
  • Phylogeny*
  • Yeasts / classification
  • Yeasts / genetics