Laparoscopic Indocyanine Green Sentinel Lymph Node Mapping in Pregnant Cervical Cancer Patients

J Minim Invasive Gynecol. 2016 Feb 1;23(2):270-3. doi: 10.1016/j.jmig.2015.10.001. Epub 2015 Oct 23.

Abstract

We present cases of 2 pregnant patients with early-stage cervical cancer who have undergone indocyanine green (ICG) sentinel lymph node (SLN) mapping followed by laparoscopic SLN biopsy, pelvic lymphadenectomy, and cervical conization. Eight milliliters of ICG were injected in the 4 quadrants of the cervix after having obtained an adequate pneumoperitoneum and having inspected the abdominal cavity. SLNs were identified in both hemipelvises in both patients. In the final pathologic analysis, both SLNs and non-SLNs were negative for metastatic disease. No adverse events from ICG injection were recorded. ICG SLN mapping seems to be feasible in pregnant cervical cancer patients.

Keywords: Cervical cancer; Indocyanine green; Laparoscopy; Near infrared fluorescence imaging; Pregnancy; Sentinel lymph node mapping.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Coloring Agents*
  • Conization
  • Female
  • Humans
  • Indocyanine Green*
  • Laparoscopy
  • Lymph Node Excision
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis
  • Pregnancy
  • Pregnancy Complications, Neoplastic / pathology*
  • Pregnancy Complications, Neoplastic / surgery
  • Pregnancy Outcome
  • Sentinel Lymph Node Biopsy*
  • Spectroscopy, Near-Infrared
  • Uterine Cervical Neoplasms / pathology*
  • Uterine Cervical Neoplasms / surgery

Substances

  • Coloring Agents
  • Indocyanine Green