Nation-Based Occurrence and Endogenous Biological Reduction of Mycotoxins in Medicinal Herbs and Spices

Toxins (Basel). 2015 Oct 14;7(10):4111-30. doi: 10.3390/toxins7104111.

Abstract

Medicinal herbs have been increasingly used for therapeutic purposes against a diverse range of human diseases worldwide. Moreover, the health benefits of spices have been extensively recognized in recent studies. However, inevitable contaminants, including mycotoxins, in medicinal herbs and spices can cause serious problems for humans in spite of their health benefits. Along with the different nation-based occurrences of mycotoxins, the ultimate exposure and toxicities can be diversely influenced by the endogenous food components in different commodities of the medicinal herbs and spices. The phytochemicals in these food stuffs can influence mold growth, mycotoxin production and biological action of the mycotoxins in exposed crops, as well as in animal and human bodies. The present review focuses on the occurrence of mycotoxins in medicinal herbs and spices and the biological interaction between mold, mycotoxin and herbal components. These networks will provide insights into the methods of mycotoxin reduction and toxicological risk assessment of mycotoxin-contaminated medicinal food components in the environment and biological organisms.

Keywords: aflatoxin; fumonisin; herbal medicine; mycotoxins; ochratoxin A; spice.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Drug Contamination*
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / standards
  • Food Contamination / analysis*
  • Humans
  • Mycotoxins / analysis*
  • Mycotoxins / toxicity
  • Plants, Medicinal / chemistry*
  • Plants, Medicinal / microbiology
  • Risk Assessment
  • Spices / analysis*
  • Spices / microbiology
  • Spices / standards

Substances

  • Drugs, Chinese Herbal
  • Mycotoxins