[Recent Advances in Vaccines and Drugs Against the Ebola Virus]

Bing Du Xue Bao. 2015 May;31(3):287-92.
[Article in Chinese]

Abstract

The Ebola virus belongs to the Filovirus family, which causes Ebola hemorrhagic fever (mortality, 25%-90%). An outbreak of infection by the Ebola virus is sweeping across West Africa, leading to high mortality and worldwide panic. The Ebola virus has caused a serious threat to public health, so intensive scientific studies have been carried out. Several vaccines (e.g., rVSV-ZEBOV, ChAd3-ZEBOV) have been put into clinical trials and antiviral drugs (e.g., TKM-Ebola, ZMAPP) have been administered in the emergency setting to patients infected by the Ebola virus. Here, recent advances in vaccines and drugs against the Ebola virus are reviewed.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antiviral Agents / administration & dosage*
  • Ebola Vaccines / administration & dosage
  • Ebola Vaccines / genetics
  • Ebola Vaccines / immunology*
  • Ebolavirus / drug effects
  • Ebolavirus / genetics
  • Ebolavirus / immunology
  • Ebolavirus / physiology*
  • Hemorrhagic Fever, Ebola / drug therapy*
  • Hemorrhagic Fever, Ebola / prevention & control
  • Hemorrhagic Fever, Ebola / virology
  • Humans

Substances

  • Antiviral Agents
  • Ebola Vaccines