Current Options for the Treatment of Food Allergy

Pediatr Clin North Am. 2015 Dec;62(6):1531-49. doi: 10.1016/j.pcl.2015.07.015. Epub 2015 Sep 7.

Abstract

Food allergy is increasing in prevalence; as a result, there is intense focus on developing safe and effective therapies. Current methods of specific immunotherapy include oral, sublingual, and epicutaneous, while nonspecific methods that have been investigated include: Chinese herbal medicine, probiotics, and anti-IgE antibodies. Although some studies have demonstrated efficacy in inducing desensitization, questions regarding safety and the potential for achieving immune tolerance remain. Although some of these therapies demonstrate promise, further investigation is required before their incorporation into routine clinical practice.

Keywords: Anaphylaxis; Desensitization; Food allergy treatment; Food allergy/hypersensitivity; Immunotherapy; Omalizumab; Probiotics; Tolerance.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Anaphylaxis / prevention & control
  • Anti-Allergic Agents / therapeutic use
  • Child
  • Desensitization, Immunologic
  • Food Hypersensitivity / therapy*
  • Humans
  • Immunotherapy / methods*
  • Omalizumab / therapeutic use
  • Patient Education as Topic
  • Probiotics / therapeutic use

Substances

  • Anti-Allergic Agents
  • Omalizumab