Micronutrient Deficiencies in Patients With Heart Failure: Relationships With Body Mass Index and Age

J Card Fail. 2015 Dec;21(12):968-72. doi: 10.1016/j.cardfail.2015.10.001. Epub 2015 Oct 9.

Abstract

Background: It is conceivable that lean patients (body mass index 18.5-24.9 kg/m(2)) with heart failure (HF) have low body weight due to low food consumption and that this may contribute to micronutrient deficiencies and to their poorer prognosis compared with overweight/obese patients. We hypothesized that lean patients have a greater number of inadequate micronutrient intakes (<50% of recommendations) than overweight/obese patients and that this also depends on age.

Methods and results: Lean (n = 15) and overweight/obese (n = 49) patients underwent 24-hour diet and physical activity recall interviews. Inadequate essential micronutrient intakes were ubiquitous (intakes of 13 ± 1 of 27 micronutrients were inadequate) and did not depend on race, status, or access to supermarkets. Younger (40-64 y) lean patients had inadequate intakes of 20 ± 2 micronutrients, which was more than the other weight/age subgroups (all P < .01). Physical activity levels did not differ across weight and age groups.

Conclusions: Patients with HF may be at risk of malnutrition due to numerous inadequate micronutrient intakes; younger lean patients may have an especially high risk. Future studies are needed to confirm these preliminary findings and to investigate the possibility that incorporating a micronutrient-dense meal plan will improve patient outcomes.

Keywords: Heart failure; micronutrients; nutrition.

Publication types

  • Comparative Study
  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Body Mass Index*
  • Body Weight
  • Cross-Sectional Studies
  • Diet
  • Energy Intake*
  • Female
  • Heart Failure / epidemiology*
  • Heart Failure / physiopathology
  • Humans
  • Life Style
  • Male
  • Malnutrition / epidemiology
  • Malnutrition / physiopathology
  • Micronutrients / deficiency*
  • Middle Aged
  • Motor Activity / physiology*
  • Nutrition Assessment
  • Obesity / epidemiology*
  • Obesity / physiopathology
  • Prognosis
  • Reference Values

Substances

  • Micronutrients