Role of Negative-Pressure Wound Therapy in the Management of Submandibular Fistula After Reconstruction for Osteoradionecrosis

J Oral Maxillofac Surg. 2016 Feb;74(2):401-5. doi: 10.1016/j.joms.2015.09.012. Epub 2015 Sep 25.

Abstract

Purpose: Although negative-pressure wound therapy (NPWT) for complicated wounds has been extensively studied, it is rarely used in cases involving a submandibular fistula due to radiation-induced osteoradionecrosis of the mandible. This study aimed to investigate the efficacy of NPWT for submandibular fistulas after reconstruction for osteoradionecrosis.

Patients and methods: Nine patients with submandibular fistulas after reconstruction for osteoradionecrosis treated with NPWT between 2011 and 2014 were included in the study. The wound healing was documented.

Results: The NPWT device was removed postoperatively between days 7 and 12 (mean duration, 9.6 days). The wound bed was filled with healthy granulation tissue, and successful healing by second intention was observed in all patients within 2 weeks. No complications were observed. The follow-up ranged from 4 to 27 months (mean, 18 months); the fistulas exhibited excellent healing, and no recurrence or infection was observed.

Conclusions: NPWT is a safe, effective technique for managing submandibular fistulas after reconstruction for osteoradionecrosis.

MeSH terms

  • Aged
  • Bone Plates
  • Bone Transplantation / methods
  • Device Removal
  • Female
  • Follow-Up Studies
  • Free Tissue Flaps / transplantation
  • Graft Survival
  • Humans
  • Male
  • Mandibular Diseases / surgery*
  • Mandibular Reconstruction / instrumentation
  • Mandibular Reconstruction / methods*
  • Middle Aged
  • Myocutaneous Flap / transplantation
  • Nasopharyngeal Neoplasms / radiotherapy
  • Negative-Pressure Wound Therapy / methods*
  • Osteoradionecrosis / surgery*
  • Pectoralis Muscles / transplantation
  • Salivary Gland Fistula / therapy*
  • Submandibular Gland Diseases / therapy*
  • Surgical Wound Dehiscence / etiology
  • Wound Healing / physiology