Case report: a diagnostically challenging conjunctival mass caused by the Epstein-Barr virus

BMC Ophthalmol. 2015 Oct 7:15:129. doi: 10.1186/s12886-015-0111-2.

Abstract

We present a paediatric case of infectious mononucleosis in a 13-year old, manifesting with follicular conjunctivitis and a conjunctival mass in one eye with no evidence of leucocytosis on the blood count. The diagnosis was confirmed following surgical excision and biopsy. The case represented a diagnostic challenge due to its atypism and given the steady increase in the prevalence of EBV-related ocular diseases in the last years, this report can serve as an example to prompt earlier serological tests to identify the aetiology in similar cases. This is important because EBV can be treated with acyclovir early in the active viral phase.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antibodies, Viral / blood
  • Conjunctivitis, Viral / diagnosis*
  • Conjunctivitis, Viral / surgery
  • Conjunctivitis, Viral / virology
  • Epstein-Barr Virus Infections / diagnosis*
  • Epstein-Barr Virus Infections / surgery
  • Epstein-Barr Virus Infections / virology
  • Epstein-Barr Virus Nuclear Antigens / immunology
  • Eye Infections, Viral / diagnosis*
  • Eye Infections, Viral / surgery
  • Eye Infections, Viral / virology
  • Humans
  • Immunoglobulin G / blood
  • Infectious Mononucleosis / diagnosis
  • Infectious Mononucleosis / surgery
  • Infectious Mononucleosis / virology
  • Male
  • Ophthalmologic Surgical Procedures

Substances

  • Antibodies, Viral
  • Epstein-Barr Virus Nuclear Antigens
  • Immunoglobulin G