Presumed Perinatal Stroke: Risk Factors, Clinical and Radiological Findings

J Child Neurol. 2016 Apr;31(5):621-8. doi: 10.1177/0883073815609149. Epub 2015 Oct 7.

Abstract

It is unknown why some infants with perinatal stroke present clinical symptoms late during infancy and will be identified as infants with presumed perinatal stroke. The risk factors and clinical and radiological data of 42 infants with presumed perinatal stroke (69% with periventricular venous infarction and 31% with arterial ischemic stroke) from the Estonian Pediatric Stroke Database were reviewed. Children with presumed perinatal stroke were born at term in 95% of the cases and had had no risk factors during pregnancy in 43% of the cases. Children with periventricular venous infarction were born significantly more often (82%) vaginally (P = .0213) compared to children with arterial stroke (42%); nor did they require resuscitation (P = .0212) or had any neurological symptoms after birth (P = .0249). Periventricular venous infarction is the most common type of lesion among infants with the presumed perinatal stroke. Data suggest that the disease is of prenatal origin.

Keywords: CT; MRI; pediatric stroke; perinatal stroke; presumed perinatal stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Factual / statistics & numerical data
  • Estonia / epidemiology
  • Female
  • Gestational Age
  • Humans
  • Image Processing, Computer-Assisted
  • Infant
  • Magnetic Resonance Imaging*
  • Male
  • Pregnancy
  • Prenatal Diagnosis
  • Risk Factors
  • Stroke / diagnostic imaging*
  • Stroke / epidemiology