Detection of Site-Specific Blood Flow Variation in Humans during Running by a Wearable Laser Doppler Flowmeter

Sensors (Basel). 2015 Oct 5;15(10):25507-19. doi: 10.3390/s151025507.

Abstract

Wearable wireless physiological sensors are helpful for monitoring and maintaining human health. Blood flow contains abundant physiological information but it is hard to measure blood flow during exercise using conventional blood flowmeters because of their size, weight, and use of optic fibers. To resolve these disadvantages, we previously developed a micro integrated laser Doppler blood flowmeter using microelectromechanical systems technology. This micro blood flowmeter is wearable and capable of stable measurement signals even during movement. Therefore, we attempted to measure skin blood flow at the forehead, fingertip, and earlobe of seven young men while running as a pilot experiment to extend the utility of the micro blood flowmeter. We measured blood flow in each subject at velocities of 6, 8, and 10 km/h. We succeeded in obtaining stable measurements of blood flow, with few motion artifacts, using the micro blood flowmeter, and the pulse wave signal and motion artifacts were clearly separated by conducting frequency analysis. Furthermore, the results showed that the extent of the changes in blood flow depended on the intensity of exercise as well as previous work with an ergometer. Thus, we demonstrated the capability of this wearable blood flow sensor for measurement during exercise.

Keywords: MEMS; blood flow; exercise; laser Doppler; wearable sensor.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Flowmeters
  • Hemodynamics
  • Humans
  • Laser-Doppler Flowmetry / instrumentation*
  • Laser-Doppler Flowmetry / methods
  • Male
  • Micro-Electrical-Mechanical Systems
  • Mobile Applications
  • Monitoring, Ambulatory / instrumentation*
  • Regional Blood Flow / physiology*
  • Rheology
  • Running / physiology*
  • Telemetry / instrumentation
  • Young Adult