Ultrasensitive self-powered cytosensors based on exogenous redox-free enzyme biofuel cells as point-of-care tools for early cancer diagnosis

Chem Commun (Camb). 2015 Dec 7;51(94):16763-6. doi: 10.1039/c5cc07520c.

Abstract

An exogenous redox-free, membrane-less enzyme biofuel cell-based ultrasensitive self-powered cytosensing platform was fabricated. With the ultrahigh sensitivity and the merits of not requiring external power sources or exogenous reagents, the device has great potential as a point-of-care tool for early diagnosis of cancer in vivo.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bioelectric Energy Sources*
  • Biosensing Techniques*
  • Diagnostic Techniques and Procedures / instrumentation*
  • Diagnostic Techniques and Procedures / standards
  • Electrochemical Techniques / instrumentation
  • Humans
  • Limit of Detection
  • Neoplasms / diagnosis*
  • Oxidation-Reduction
  • Oxidoreductases Acting on CH-CH Group Donors / metabolism
  • Point-of-Care Systems*

Substances

  • Oxidoreductases Acting on CH-CH Group Donors
  • bilirubin oxidase