Lipid Profiles and Signals for Long Life

Trends Endocrinol Metab. 2015 Nov;26(11):589-592. doi: 10.1016/j.tem.2015.08.007. Epub 2015 Oct 1.

Abstract

Historically, fat was considered detrimental to health and lifespan. However, lipidomics, the quantification of all lipid molecules in a biological sample, and genetic studies in model organisms are revealing specific fats that may promote longevity. These emerging findings provide insight into the complex relationship between lipids and longevity.

Keywords: aging; lipid signaling; lipidomics.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Aging / metabolism*
  • Animals
  • Humans
  • Lipid Metabolism / physiology*
  • Signal Transduction / physiology*