Hypertrophic pachymeningitis accompanying neuromyelitis optica spectrum disorder: A case report

Abstract

We report a case of idiopathic cerebral hypertrophic pachymeningitis accompanying neuromyelitis optica spectrum disorder. No other identifiable cause of pachymeningitis was detected. Corticosteroid therapy was effective for both diseases. Hypertrophic pachymeningitis is closely related to autoimmune inflammatory disease of the central nervous system. This case supports the hypothesis that hypertrophic pachymeningitis can be a rare comorbidity of neuromyelitis optica spectrum disorder.

Keywords: Aquaporin-4 antibody; Autoimmune disease; Hypertrophic pachymeningitis; Neuromyelitis optica; Neuromyelitis optica spectrum disorders.